The Journal of allergy and clinical immunology
-
J. Allergy Clin. Immunol. · Oct 1999
Multicenter StudyThe relationships among environmental allergen sensitization, allergen exposure, pulmonary function, and bronchial hyperresponsiveness in the Childhood Asthma Management Program.
Sensitivity and exposure to indoor allergens constitutes a risk factor for the development and persistence of asthma in children. ⋯ Sensitivity to dog or cat dander or Alternaria by skin testing was associated with increased bronchial responsiveness but not decreased lung function in children with mild to moderate asthma. These findings support the important role that sensitization to certain allergens plays in modulating bronchial responsiveness.