The Journal of allergy and clinical immunology
-
J. Allergy Clin. Immunol. · Feb 2004
Multicenter StudyMulticenter study of emergency department visits for food allergies.
Relatively little is known about the characteristics of patients who visit the emergency department (ED) for an acute allergic reaction. Although anaphylaxis guidelines suggest treatment with epinephrine, teaching about self-injectable epinephrine, and referral to an allergist, current ED management remains uncertain. ⋯ Although guidelines suggest specific approaches for the management of acute allergic reactions, ED concordance for food allergy appears low. These findings support a new collaboration between professional organizations in allergy and emergency medicine and the development of educational programs and materials for ED patients and staff.
-
J. Allergy Clin. Immunol. · Feb 2004
Comparative Study Clinical TrialLeukotrienes and 8-isoprostane in exhaled breath condensate of children with stable and unstable asthma.
Cysteinyl-leukotrienes (cys-LTs) and 8-isoprostane are biomarkers of airway inflammation and oxidative stress. ⋯ Our study shows that EBC cys-LTs and 8-isoprostane concentrations are higher in asthmatic children than in healthy control children, with scattered values in patients with unstable asthma. These findings suggest that EBC eicosanoid measurement may have useful clinical implications for investigating phenotype differences among asthmatic patients.