The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Aug 2005
Duration of postviral airway hyperresponsiveness in children with asthma: effect of atopy.
Respiratory viruses induce asthma exacerbations and airway hyperresponsiveness (AHR). Atopy is an important risk factor for asthma persistence. ⋯ In asthmatic children the duration of AHR after a single natural cold is 5 to 11 weeks. However, an increased rate of symptomatic cold and asthma episodes in atopic children is associated with considerable cumulative prolongation of AHR, which might help explain the role of atopy as a risk factor for asthma persistence.