The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Apr 2006
Randomized Controlled Trial Multicenter StudySublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis.
Specific immunotherapy is the only treatment modality that has the potential to alter the natural course of allergic diseases. Sublingual immunotherapy has been developed to facilitate access to this form of treatment and to minimize serious adverse events. ⋯ For patients with grass pollen allergy, sublingual immunotherapy is well tolerated and can reduce symptoms and improve quality of life.
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J. Allergy Clin. Immunol. · Apr 2006
Randomized Controlled TrialEffect of codeine on objective measurement of cough in chronic obstructive pulmonary disease.
Codeine is the standard antitussive treatment to which novel agents are compared. Little is known about the objective effect of any treatments on cough in chronic obstructive pulmonary disease (COPD). ⋯ Codeine is the antitussive agent to which we compare new treatments; however, in a group of stable patients with COPD, it had no effect on cough frequency over placebo.