The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Dec 2009
Randomized Controlled Trial Multicenter StudyOmalizumab for the treatment of exacerbations in children with inadequately controlled allergic (IgE-mediated) asthma.
Many children with asthma continue to experience symptoms despite available therapies. ⋯ Add-on omalizumab is effective and well tolerated as maintenance therapy in children (6 to <12 years) with moderate-to-severe persistent allergic (IgE-mediated) asthma whose symptoms are inadequately controlled despite medium to high doses of ICSs.
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J. Allergy Clin. Immunol. · Dec 2009
Epinephrine treatment is infrequent and biphasic reactions are rare in food-induced reactions during oral food challenges in children.
Data about epinephrine use and biphasic reactions in childhood food-induced anaphylaxis during oral food challenges are scarce. ⋯ Older age and reactions to peanuts were risk factors for anaphylaxis during oral food challenges. Reactions requiring multiple doses of epinephrine and biphasic reactions were infrequent.