The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Jul 2009
Sublingual immunotherapy for allergic respiratory diseases: an evaluation of meta-analyses.
Five published meta-analyses (MAs) seem to prove the efficacy of sublingual immunotherapy in allergic asthma and rhinoconjunctivitis. ⋯ Because of discrepancies, inconsistencies, and lack of robustness, the MAs on sublingual immunotherapy do not provide enough evidence to support its current routine management in patients with allergic asthma or rhinoconjunctivitis. Sensitivity to potential publication bias should be tested and reported in all MAs.