The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Jun 2011
Multicenter Study Comparative StudyObesity and asthma: an association modified by age of asthma onset.
Studies of asthma phenotypes have identified obesity as a component of a group characterized by a high proportion of subjects with adult-onset asthma. However, whether age of asthma onset modifies the association between obesity and asthma is unknown. ⋯ Asthmatic subjects are differentially affected by obesity based on whether they had asthma early (<12 years of age) or later in life. These results highlight the need to understand obesity as a comorbidity that affects specific clinical phenotypes and not all asthma subjects alike.