The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · May 2012
Relationship between red meat allergy and sensitization to gelatin and galactose-α-1,3-galactose.
We have observed patients clinically allergic to red meat and meat-derived gelatin. ⋯ Most patients allergic to red meat were sensitized to gelatin, and a subset was clinically allergic to both. The detection of α-Gal in gelatin and correlation between the results of α-Gal and gelatin testing raise the possibility that α-Gal IgE might be the target of reactivity to gelatin. The pathogenic relationship between tick bites and sensitization to red meat, α-Gal, and gelatin (with or without clinical reactivity) remains uncertain.
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J. Allergy Clin. Immunol. · May 2012
Age-related differences in clinical outcomes for acute asthma in the United States, 2006-2008.
Little is known about the effect of age on acute asthma outcomes. ⋯ Older adults with acute asthma have a substantial burden of morbidity and mortality. With the US population aging, there is an urgent need for targeted interventions for this high-risk population.