The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Apr 2021
Randomized Controlled TrialEffect of early and late prenatal vitamin D and maternal asthma status on offspring asthma or recurrent wheeze.
Childhood asthma developmental programming is complex. Maternal asthma is a strong risk factor for childhood asthma, whereas vitamin D (VD) has emerged as a modifiable prenatal exposure. ⋯ This study implies a protective role for VD sufficiency throughout pregnancy, particularly in attenuating the risk conferred by maternal asthma on childhood asthma or recurrent wheeze development.