The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Jul 2021
Maternal stress and depression are associated with respiratory phenotypes in urban children.
Prenatal and early-life exposure to maternal stress and depression is linked to development of recurrent wheezing in young children. ⋯ Among high-risk, urban children, maternal stress and depression in early life were positively associated with respiratory illnesses and a moderate-wheeze-low-atopy phenotype. These results suggest that treating stress and depression in expectant and new mothers could reduce viral respiratory illnesses and recurrent wheeze during the preschool years and some forms of childhood asthma.