The Journal of allergy and clinical immunology
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J. Allergy Clin. Immunol. · Mar 2007
Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica.
Little is known about sensitization (defined as a positive IgE) to helminths and disease severity in patients with asthma. ⋯ In areas with a low prevalence of helminthiasis such as Costa Rica, Ascaris sensitization may be an important marker of severe atopy and disease morbidity in children with asthma.
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J. Allergy Clin. Immunol. · Mar 2007
Cat IgA, representative of new carbohydrate cross-reactive allergens.
Allergens from cat are among the most potent elicitors of allergic disease. Four cat allergens have been identified; however, evidence indicates the existence of additional allergens. ⋯ This new group of cross-reactive carbohydrate IgE epitopes should be taken into consideration when diagnosing patients with suspected animal allergy.
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J. Allergy Clin. Immunol. · Feb 2007
Meta AnalysisDifferential effects of maintenance long-acting beta-agonist and inhaled corticosteroid on asthma control and asthma exacerbations.
Combination therapy with long-acting beta-agonists (LABAs)/inhaled corticosteroids (ICSs) has become established as effective maintenance treatment for asthma. ⋯ The greatest benefit and least harm of LABAs comes when they are added to a similar ICS dose in adults with symptomatic asthma.
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J. Allergy Clin. Immunol. · Feb 2007
Prevalence of viral respiratory tract infections in children with asthma.
Previous studies support a strong association between viral respiratory tract infections and asthma exacerbations. The effect of newly discovered viruses on asthma control is less well defined. ⋯ These results support the need for therapies effective against rhinovirus as a means to decrease asthma exacerbations.
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J. Allergy Clin. Immunol. · Jan 2007
Randomized Controlled TrialEgg oral immunotherapy in nonanaphylactic children with egg allergy.
There is no current active treatment for food allergy. Traditional injection immunotherapy has been proved unsafe, and thus there is a need for other forms of immunotherapy. ⋯ Use of allergen-specific OIT to protect subjects with food allergy from reaction on accidental ingestion would represent a significant paradigm change in the treatment of food allergy.