Anesthesiology
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Randomized Controlled Trial Comparative Study Clinical Trial
A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children.
In children, opioids are valuable both for their analgesic properties and for their salutary effect on emergence delirium. Although intraoperative administration of opioids is often cited as the cause of postoperative emesis, few data quantitating the magnitude of this effect exist. ⋯ For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery.
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Multicenter Study Comparative Study Clinical Trial
Multisite evaluation of a continuous intraarterial blood gas monitoring system.
We compared the performance of a new, continuous intraarterial blood gas (CIABG) monitor with arterial values obtained periodically and analyzed by conventional equipment. ⋯ Over the range of values and under the clinical conditions studied, CIABG monitoring provides immediate blood gas results and trend information with sufficient agreement with in vitro results to be reliable for decision making in most clinical circumstances. Generally, the differences in the values between the two methods of analysis were the result of the combination of the inherent errors of each method. Additional studies need to be undertaken to evaluate the performance of the CIABG monitor across wider ranges of blood gas values, especially for arterial PO2 values less than 60 mmHg and arterial PCO2 values greater than 50 mmHg.