Anesthesiology
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Letter Case Reports
Perioperative extrapyramidal reactions associated with ondansetron.
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Randomized Controlled Trial Clinical Trial
Reducing myoclonus after etomidate.
The authors hypothesized that myoclonus after etomidate is dose-related, could be suppressed when small doses of etomidate were administered before induction, and is unassociated with seizure-like activity on electroencephalogram (EEG). ⋯ Incidence and intensity of myoclonus after induction with etomidate are dose-related, suppressed by pretreatment, and unassociated with seizure-like EEG activity.
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Randomized Controlled Trial Clinical Trial
Targeting effect compartment or central compartment concentration of propofol: what predicts loss of consciousness?
An effect compartment has been postulated, and the ke0 has been quantified for several intravenous anesthetic drugs using electroencephalography (EEG) as the measure of effect. The authors wanted to validate that loss of responsiveness (LOR) was related to targeting an effect compartment concentration rather than a central compartment (plasma) concentration. ⋯ This study confirms the utility of the ke0 value to describe the effect compartment for propofol. The authors also illustrate the importance of selecting the correct ke0 value for the pharmacokinetic parameters used within the TCI system.
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Although the total costs of graduate medical education are difficult to quantify, this information may be of great importance for health policy and planning over the next decade. This study describes the total costs associated with the residency program at the University of Texas--Houston Department of Anesthesiology during the 1996-1997 academic year. ⋯ In most scenarios, the value of the teaching and clinical services provided by residents exceeded the cost of the resources used in the educational program.