Anesthesiology
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Clinical Trial
Using permutation entropy to measure the electroencephalographic effects of sevoflurane.
Approximate entropy (AE) has been proposed as a measure of anesthetic drug effect in electroencephalographic data. Recently, a new method called permutation entropy (PE) based on symbolic dynamics was also proposed to measure the complexity in an electroencephalographic series. In this study, the AE and PE were applied to electroencephalographic recordings for revealing the effect of sevoflurane on brain activity. The dose-response relation of PE during sevoflurane anesthesia was compared with that of AE. ⋯ The results show that PE can estimate the sevoflurane drug effect more effectively than AE. This method could be applied to design a new electroencephalographic monitoring system to estimate sevoflurane anesthetic drug effect.
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Biography Historical Article
Zeljko J. Bosnjak, Ph.D., recipient of the 2008 Excellence in Research Award.