Anesthesiology
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Randomized Controlled Trial Multicenter Study
A perioperative smoking cessation intervention with varenicline: a double-blind, randomized, placebo-controlled trial.
The efficacy of perioperative tobacco interventions on long-term abstinence and the safety of smoking cessation less than 4 weeks before surgery is unclear. Our objective was to determine the efficacy and safety of a perioperative smoking cessation intervention with varenicline to reduce smoking in elective surgical patients. ⋯ A perioperative smoking cessation intervention with varenicline increased abstinence from smoking 3, 6, and 12 months after elective noncardiac surgery with no increase in serious adverse events.