Clinica chimica acta; international journal of clinical chemistry
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Comparative Study
The correlation between human plasma melatonin levels and urinary 6-hydroxymelatonin excretion.
A significant correlation (0.76) has been found between nighttime peak plasma melatonin levels and the 24-h urinary excretion totals for conjugated 6-hydroxymelatonin for a group of 22 women. This study validates the comparison of plasma levels of the hormone or urinary levels of its metabolite to assess pineal gland production of melatonin in humans.