Neuroradiology
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Reversible focal lesions in the splenium of the corpus callosum (SCC) have recently been reported. They are circumscribed and located in the median aspect of the SCC. On MRI, they are hyperintense on T2-W and iso-hypointense on T1-W sequences, with no contrast enhancement. ⋯ Edema and diffusion restriction in focal reversible lesions of the SCC have been attributed to excitotoxic mechanisms that can result from different mechanisms; no unifying relationship has been found to explain all the pathologies associated with SCC lesions. In our opinion, the similar imaging, clinical and prognostic aspects of these lesions depend on a high vulnerability of the SCC to excitotoxic edema and are less dependent on the underlying pathology. In this review, the relevant literature concerning reversible focal lesions in the SCC is analyzed and hypotheses about their pathogenesis are proposed.
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Stable insertion of guide catheters via the femoral route can prove difficult because of tortuous vasculature leading to failure of endovascular treatment of intracranial aneurysms. ⋯ The use of a long introducer sheath, by enhancing stability in the aortic arch and supraaortic vessels, provides another solution to the problem of vascular tortuosity that hinders endovascular treatment of intracranial lesions.