Der Urologe. Ausg. A
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This review summarizes results of neoadjuvant and adjuvant trials for locally advanced bladder cancer as well as data on systemic chemotherapy for metastatic urothelial cancer. Increasing attention has been drawn to targeted cancer therapies in the treatment of urothelial cancer in recent years. In future, molecular profiling will play a major role as a means to tailor individual therapy.
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Der Urologe. Ausg. A · Oct 2010
[Sacral neuromodulation in urology. The emperor's new clothes or effective high-tech medicine?].
Sacral nerve modulation (SNM) is an innovative, minimally invasive treatment that uses chronic low-level electrical stimulation of the sacral plexus to recruit residual physiological function of urinary bladder detrusor, pelvic floor muscles, and the anorectal continence structures. Classic indications for sacral neuromodulation in urology are refractory overactive bladder symptoms (urinary urgency ± incontinence) and chronic nonobstructive urinary retention. SNM also offers a therapeutic alternative in refractory chronic pelvic pain syndrome. ⋯ To date, no information on the number of implanted stimulators in Germany is available. This suggests the need for establishment of a national prospective registry. It would also be appropriate that the experts from the implantation centers form a working group.
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Der Urologe. Ausg. A · Sep 2010
Biography Historical Article[Urology and National Socialism: the fate of Alexander von Lichtenberg 1880-1949].
Alexander von Lichtenberg (1880-1949) was one of the famous members of the German Urological Society (DGU) in pre-war Germany. He introduced excretion urography and a special TURP Instrument. In 1928 he was president of the 8th meeting held in the German capital Berlin. ⋯ Even in Hungary, his native country, he again had to resist anti-Semitic hostility. Later on he lived in Mexico. Alexander von Lichtenberg has to be remembered with special focus on the exodus of German Jewish scientists during the Nazi time.
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Der Urologe. Ausg. A · Aug 2010
Historical Article[Urology in a museum: 10 years in Düsseldorf : Living history of medicine in the Museum and Archive for Urology of the German Society of Urology].
The Urology History Center of the German Society of Urology is dedicated to the study of the medical past through a distinguished collection of rare books, museum artifacts, archives, and images. The Museum and Archive represent the history of urology and the development of the specialty through the ages with emphasis on the development in the German-speaking countries in Europe. ⋯ Documents and photographs provide a unique glimpse of the past. The general public and medical professionals or urologists are intrigued by this display of artifacts related to urology.
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Der Urologe. Ausg. A · Feb 2010
Review[Second-line therapy of idiopathic detrusor overactivity. Sacral neuromodulation and botulinum toxin A].
The syndrome of idiopathic overactive bladder (I-OAB) impairs quality of life for the affected individuals. Conservative treatment options such as antimuscarinics are not always effective, and resulting side effects can lead the patient to stop treatment. ⋯ Currently, the approved treatment option for I-OAB that is recommended by the International Consultation on Incontinence is sacral neuromodulation by InterStim therapy. This article gives an overview of the present clinical evidence on the effectiveness and reliability of these two treatment modalities as well as the current significance of sacral neuromodulation and botulinum toxin A for the second-line treatment of adult I-OAB.