Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Aug 1996
Randomized Controlled Trial Comparative Study Clinical TrialControlled clinical study of skin donor sites and deep partial-thickness burns treated with cultured epidermal allografts.
Two clinical studies in donor sites and deep partial-thickness burns treated with banked cultured human epidermal allografts are described. Ten burn patients were subjected to donor split-thickness skin harvesting. The study was controlled, side-by-side comparative, blind, and randomized. ⋯ Wounds treated with cultured allografts showed complete reepithelialization in about 3 to 6 days. The two clinical studies showed that banked cultured epidermal allograft promotes a significantly faster epithelialization of donor sites and deep partial-thickness wounds. These results support the idea that cultured allografts should be used routinely to improve treatment of burn patients and reduce their therapy time.