Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Nov 2011
Comparative StudyPostoperative enoxaparin prevents symptomatic venous thromboembolism in high-risk plastic surgery patients.
Venous thromboembolism is a major patient safety issue. The Plastic Surgery Foundation-sponsored Venous Thromboembolism Prevention Study examined whether postoperative enoxaparin prevents symptomatic venous thromboembolism in adult plastic surgery patients. ⋯ Therapeutic, III.
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Plast. Reconstr. Surg. · Nov 2011
Comparative StudyChanging practice: implementation of a venous thromboembolism prophylaxis protocol at an academic medical center.
The Institute of Medicine has identified a "quality chasm" between existing evidence and actual clinical practice. The Venous Thromboembolism Prevention Study has shown that enoxaparin prophylaxis is a safe and effective way of preventing postoperative venous thromboembolism. This article presents a "how-to" guide for implementation of a venous thromboembolism prophylaxis protocol. ⋯ This article provides readers with a practical approach for implementation of a venous thromboembolism prophylaxis protocol at their hospital.
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Plast. Reconstr. Surg. · Nov 2011
Reconstructive outcomes in patients undergoing contralateral prophylactic mastectomy.
As the rate of contralateral prophylactic mastectomy in breast cancer patients increases, more women are seeking immediate bilateral breast reconstruction. The authors evaluated complication rates in the index and prophylactic breasts in patients undergoing bilateral immediate reconstruction. ⋯ Therapeutic, III.
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Plast. Reconstr. Surg. · Nov 2011
Comparative StudyRegenerative surgery in cranioplasty revisited: the role of adipose-derived stem cells and BMP-2.
Reconstruction of the pediatric calvaria is frequently complicated by a shortage of bone. This problem is most apparent between 2 and 10 years of age, when the osteogenic potential of the dura is diminished and the diploic space has not matured to the point that split-thickness calvarial grafting is practical. In this article, the authors evaluate and compare the relative efficacy of adipose-derived stem cells, bone morphogenetic protein (BMP)-2, and adipose-derived stem cells osteoinduced with BMP-2 in addressing these defects. ⋯ BMP-2-based tissue engineering is a viable approach to craniofacial reconstruction. Adipose-derived stem cells did not significantly augment this process as modeled here. Advances in the understanding of craniofacial biology, and of protein- and cell-based therapies, will enhance the efficacy of tissue-engineering strategies for this problem in the future.