Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Oct 2013
Autologous immediate cranioplasty with vascularized bone in high-risk composite cranial defects.
Composite cranial defects in the setting of infection, irradiation, or cerebrospinal fluid leak present a significant risk for devastating neurologic sequelae. Such defects require soft-tissue coverage and skeletal reconstruction that can withstand the hostile environment of a precarious wound. ⋯ Therapeutic, IV.
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Plast. Reconstr. Surg. · Oct 2013
The role of chronic and perioperative glucose management in high-risk surgical closures: a case for tighter glycemic control.
The exact risk that poor glucose control introduces to patients undergoing surgical closure has yet to be fully defined. ⋯ Risk, II.
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Plast. Reconstr. Surg. · Oct 2013
Complete horizontal skin cell resurfacing and delayed vertical cell infiltration into porcine reconstructive tissue matrix compared to bovine collagen matrix and human dermis.
Xenogenous dermal matrices are used for hernia repair and breast reconstruction. Full-thickness skin replacement is needed after burn or degloving injuries with exposure of tendons or bones. The authors used a human skin organ culture model to study whether porcine reconstructive tissue matrix (Strattice) is effective as a dermal tissue replacement. ⋯ Matrix texture and surface properties governed cellular performance on tissues. Although dense dermal compaction delayed vertical cellular ingrowth for Strattice, it allowed uncompromised horizontal resurfacing. Dense dermal compaction may slow matrix decomposition and result in prolonged biomechanical stability of the graft. Reconstructive surgeons should choose the adequate matrix substitute depending on biomechanical requirements at the recipient site. Strattice may be suitable as a dermal replacement at recipient sites with high mechanical load requirements.
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Plast. Reconstr. Surg. · Oct 2013
Clinical TrialTreatment of keloids and hypertrophic scars with bleomycin and electroporation.
Keloids and hypertrophic scars are the result of abnormal healing responses and dermal tissue proliferation; current surgical procedures can give rise to exuberant scarring and permanent functional loss or disfigurement. Considering the promising results reported when treating keloids and hypertrophic scars with intralesional bleomycin injection and the enhanced effect of bleomycin when combined with electroporation, the authors hypothesized that electrochemotherapy should be used to treat keloids and hypertrophic scars when other treatments have failed. ⋯ Therapeutic, IV.
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Plast. Reconstr. Surg. · Oct 2013
ReviewHigh-pressure injection injuries in the hand: current treatment concepts.
High-pressure injection injury to the hand and upper extremity is a rare but very serious clinical entity. The objective of this article was to review the current available literature and highlight important topics. ⋯ High-pressure injection injuries to the hand can result in permanent impairment. Proper diagnosis and urgent treatment are essential for a good outcome.