Seminars in arthritis and rheumatism

The most recent articles from: Semin. Arthritis Rheum. April 2017

Semin. Arthritis Rheum. · Apr 2017

Multicenter Study Comparative Study

A multicenter, open-label, comparative study of B-cell depletion therapy with Rituximab for systemic sclerosis-associated interstitial lung disease.

Rituximab (RTX) may favorably affect lung function and skin fibrosis in patients with systemic sclerosis (SSc). We aimed to assess long-term efficacy and safety of RTX in SSc compared to standard treatment. ⋯ Our data indicate that RTX has a beneficial effect on lung function and skin fibrosis in patients with SSc. Randomized controlled studies are highly needed.

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