Anesthesia and analgesia
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Anesthesia and analgesia · Jul 1979
Comparative StudyPhysiologic effects of deep hypothermia and microwave rewarming: possible application for neonatal cardiac surgery.
Deep hypothermia (20 C) without cardiopulmonary bypass is a valuable technique during cardiac surgery in infants but rewarming of the heart following circulatory arrest and cardiac repair has traditionally been a lengthy and difficult process. In experimental animals rewarming the heart with microwave energy, as reported in this work, warms the heart before warming the periphery. ⋯ Blood pressure and arterial gases remained adequate. Microwave rewarming appears to be a useful method for reestablishment of cardiac function and normothermia following deep hypothermia.
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Under conditions of temperature and pressure commonly found in operating rooms, the anesthetics enflurane, halothane, and isoflurane act as nearly ideal gasses even at concentrations producing a saturated vapor phase. The deviations from ideality are 3.44 +/- 0.44% (SEM) for enflurane, 0.94 +/- 0.30% for halothane, and 2.96 +/- 0.29% for isoflurane. That is, 0.9 to 3.4% more anesthetic is vaporized than would be predicted from the vapor pressure of these agents.