Anesthesia and analgesia
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Anesthesia and analgesia · Jan 2007
Randomized Controlled TrialMonitoring brain oxygen saturation during coronary bypass surgery: a randomized, prospective study.
Cerebral deoxygenation is associated with various adverse systemic outcomes. We hypothesized, by using the brain as an index organ, that interventions to improve cerebral oxygenation would have systemic benefits in cardiac surgical patients. ⋯ Monitoring cerebral rSO2 in coronary artery bypass patients avoids profound cerebral desaturation and is associated with significantly fewer incidences of major organ dysfunction.
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Anesthesia and analgesia · Jan 2007
Meta AnalysisPerioperative beta-blockers for preventing surgery-related mortality and morbidity: a systematic review and meta-analysis.
Perioperative beta-blockers are suggested to reduce cardiovascular mortality, myocardial-ischemia/infarction, and supraventricular arrhythmias after surgery. We reviewed the evidence regarding the effectiveness of perioperative beta-blockers for improving patient outcomes after cardiac and noncardiac surgery. ⋯ Beta-blockers reduced perioperative arrhythmias and myocardial ischemia, but they had no effect on myocardial infarction, mortality, or length of hospitalization.
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Anesthesia and analgesia · Jan 2007
Controlled Clinical TrialIntravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma.
Although prophylactic IV administration of lidocaine attenuates the response to a variety of inhalation challenges, its effect on airway resistance after endotracheal intubation in patients with asthma is unclear. We tested the hypothesis that IV lidocaine attenuates intubation-evoked bronchoconstriction in patients with asthma. ⋯ IV lidocaine given after endotracheal intubation mitigates bronchoconstriction in patients with asthma.