Anesthesia and analgesia
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Anesthesia and analgesia · Jun 2010
Do intraoperative analgesics influence breast cancer recurrence after mastectomy? A retrospective analysis.
Whether intraoperative analgesics have an impact on postoperative cancer recurrence is unknown. Some investigations suggest that the opioids could favor relapse and that regional analgesia and nonsteroidal antiinflammatory drugs could improve cancer prognosis. We retrospectively reviewed our series of breast cancer surgery patients. ⋯ This retrospective analysis suggests that intraoperative administration of ketorolac decreases the risk of breast cancer relapse compared with other analgesícs.
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Anesthesia and analgesia · Jun 2010
Review article: the role of the perioperative period in recurrence after cancer surgery.
A wealth of basic science data supports the hypothesis that the surgical stress response increases the likelihood of cancer dissemination and metastasis during and after cancer surgery. Anesthetic management of the cancer patient, therefore, could potentially influence long-term outcome. ⋯ Retrospective clinical trials suggest that the addition of regional anesthesia might decrease recurrence after cancer surgery. Other factors such as blood transfusion, temperature regulation, and statin administration may also affect long-term outcome.
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Anesthesia and analgesia · Jun 2010
Editorial CommentElectrical safety in the operating room: dry versus wet.