Anesthesia and analgesia
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Anesthesia and analgesia · Jul 2011
ReviewAn assessment of subarachnoid block: a survey of 175 articles and recommendations for improvement.
Assessment of subarachnoid block, particularly the sensory component, may be incomplete and influence the conclusions of studies involving subarachnoid anesthesia, as well as their application in routine clinical practice. ⋯ These results suggest incomplete description of tools and assessment of sensory block in studies involving subarachnoid anesthesia. We propose a checklist to facilitate a more standardized evaluation of the extent of subarachnoid anesthesia.
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Anesthesia and analgesia · Jul 2011
Randomized Controlled Trial Multicenter Study Comparative StudyThe volume of blood for epidural blood patch in obstetrics: a randomized, blinded clinical trial.
Our aim in this multinational, multicenter, randomized, blinded trial was to determine the optimum of 3 volumes of autologous blood for an epidural blood patch. ⋯ Although the optimum volume of blood remains to be determined, we believe these findings support an attempt to administer 20 mL of autologous blood when treating postdural puncture headache in obstetric patients after unintentional dural puncture.
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Anesthesia and analgesia · Jul 2011
Randomized Controlled Trial Multicenter Study Comparative StudyDoes perioperative systolic blood pressure variability predict mortality after cardiac surgery? An exploratory analysis of the ECLIPSE trials.
Few studies describe an association of perioperative blood pressure stability with postoperative outcome. We tested the hypothesis that systolic blood pressure (SBP) variability in patients undergoing cardiac surgery is associated with 30-day mortality. ⋯ Perioperative blood pressure variability is associated with 30-day mortality in cardiac surgical patients, proportionate to the extent of SBP excursions outside the range of 75 to 135 mm Hg intraoperatively and 85 to 145 mm Hg pre- and postoperatively. Predicted mortality was greater for high-risk patients than for low-risk patients.
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Anesthesia and analgesia · Jul 2011
Randomized Controlled Trial Comparative StudyLean body weight scalar for the anesthetic induction dose of propofol in morbidly obese subjects.
The unique anesthetic risks associated with the morbidly obese (MO) population have been documented. Pharmacologic management of these patients may be altered because of the physiologic and anthropometric changes associated with obesity. Unfortunately, studies examining the effects of extreme obesity on the pharmacology of anesthetics have been sparse. Although propofol is the induction drug most frequently used in these patients, the appropriate induction dosing scalar for propofol remains controversial in MO subjects. Therefore, we compared different weight-based scalars for dosing propofol for anesthetic induction in MO subjects. ⋯ LBW is a more appropriate weight-based scalar for propofol infusion for induction of general anesthesia in MO subjects.