Anesthesia and analgesia
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Anesthesia and analgesia · May 2012
Meta AnalysisUnplanned endotracheal extubations in the intensive care unit: systematic review, critical appraisal, and evidence-based recommendations.
In this study, we updated the state of knowledge on unplanned tracheal extubations in the intensive care unit. We focused on the following topics: incidence, risk factors, reintubation after unplanned extubation, outcomes, and prevention. Based on this review, recommendations were made for preventing unplanned extubations. ⋯ Despite numerous publications on unplanned extubation, few studies assess preventive strategies for adverse events, and few clinical trials have assessed unplanned extubations. Recommendations are proposed based on the currently available literature.
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Anesthesia and analgesia · May 2012
Meta AnalysisPublication bias in the anesthesiology literature.
Publication bias occurs because positive finding studies are more likely to be published. The dearth of studies of negative or equivalence findings can erroneously affect future research and potentially clinical care of patients. We hypothesized that positive studies were more likely to be published than negative studies in anesthesiology journals with a higher impact and circulation. ⋯ This study reports the presence of publication bias in the anesthesiology literature especially in higher clinical trial impact factor journals. Publication bias can have potential implications for future research and the clinical care of patients. Authors should be encouraged to submit negative studies to high impact journals and the journals should be encouraged to evaluate the editorial process as the cause of publication bias.