Anesthesia and analgesia
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Anesthesia and analgesia · Mar 2013
Randomized Controlled TrialDetection of tidal recruitment/overdistension in lung-healthy mechanically ventilated patients under general anesthesia.
The volume-dependent single compartment model (VDSCM) has been applied for identification of overdistension in mechanically ventilated patients with acute lung injury. In this observational study we evaluated the use of the VDSCM to identify tidal recruitment/overdistension induced by tidal volume (Vt) and positive end-expiratory pressure (PEEP) in lung-healthy anesthetized subjects. ⋯ The distension index %E(2), derived from the VDSCM considering flow-dependencies, seems able to identify tidal recruitment/overdistension induced by Vt and PEEP independent of flow waveform in healthy lung-anesthetized patients.