Anesthesia and analgesia
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Anesthesia and analgesia · Nov 2014
Randomized Controlled TrialIntraoperative Dexamethasone and Delirium after Cardiac Surgery: A Randomized Clinical Trial.
Delirium is common after cardiac surgery and may be partly related to the systemic inflammatory response triggered by the surgery and the use of cardiopulmonary bypass. We hypothesized that intraoperative administration of high-dose dexamethasone, a drug with potent anti-inflammatory effects, would reduce the incidence of delirium at any time point during the first 4 postoperative days after cardiac surgery. ⋯ The intraoperative administration of dexamethasone did not reduce the incidence or duration of delirium in the first 4 days after cardiac surgery.
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Anesthesia and analgesia · Nov 2014
Multicenter StudyVariations in the Risk of Acute Kidney Injury Across Intraabdominal Surgery Procedures.
The literature on perioperative acute kidney injury (AKI) focuses mainly on cardiac and major vascular surgery. Among noncardiac general surgery procedures, intraabdominal general surgery has been identified as high risk for developing AKI, but variations in AKI risk and its impact on 30-day mortality among different types of abdominal surgeries are not well characterized. ⋯ The incidence of AKI and the impact of AKI on 30-day mortality vary markedly across procedures within intraabdominal general surgery. This highlights the importance of preoperative risk stratification and identifies procedure type as a significant risk factor for AKI and 30-day mortality.
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Anesthesia and analgesia · Nov 2014
Editorial CommentAnesthesiologists and substance use disorders.