Anesthesia and analgesia
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Anesthesia and analgesia · Dec 1985
Randomized Controlled Trial Clinical TrialDoes intravenous lidocaine prevent laryngospasm after extubation in children?
One hundred otherwise healthy children undergoing tonsillectomy were investigated in a double-blind study to examine the effect of intravenous lidocaine in preventing laryngospasm upon extubation. The children were anesthetized with N2O-O2-halothane and orally intubated. ⋯ Eleven children (2%) in each group of 50 developed laryngospasm. From our findings it is concluded that lidocaine, 1.5 mg/kg, does not prevent laryngospasm upon extubation when extubation is carried out at the start of swallowing activity.
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The study was undertaken to evaluate the postoperative pain control ability of ketamine injected into the epidural space. We conclude that it produces potent postoperative analgesia without major respiratory depression or other side effects.
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Several studies have shown that surgical patients cannot consciously recall or recognize events to which they had been exposed during general anesthesia. Might evidence of memory for intraoperative events be revealed through the performance of a postoperative test that does not require remembering to be deliberate or intentional? Results of the present study, involving the recognition and spelling of semantically biased homophones, suggest a negative answer to this question and imply that intraoperative events cannot be remembered postoperatively, either with or without awareness.