Atherosclerosis
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Meta Analysis
Efficacy and safety of long-term treatment with statins for coronary heart disease: A Bayesian network meta-analysis.
Our study aims to evaluate the efficacy and safety of long-term treatment of statins for coronary heart disease (CHD). ⋯ Statins significantly reduced levels of blood lipids, with a high dose of atorvastatin being the most effective in blood-lipid level modification. Statins reduced the risk of CHD mortality and all-cause mortality, with atorvastatin and fluvastatin being the most effective in reducing the risk of CHD mortality and all-cause mortality. Statins increased the risk of muscle disease and kidney damage.
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Systemic inflammation has been hypothesized as a possible mechanism of Takotsubo cardiomyopathy (TTC). Aim of the study was to assess the role of interleukin (IL)-6 and IL-10 in subjects with an episode of TTC. ⋯ Serum IL-6 and IL-10 admission levels are associated with higher risk of adverse events during follow-up.