Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · May 2002
Review Comparative Study[Determination of glycated hemoglobins (Hb A1c)].
Glycated hemoglobin is measured as HbA1c and is the result of an irreversible non-enzymatic glycation of the beta chain of hemoglobin A. HbA1c is used routinely to assess long term glycemic control in patients with diabetes mellitus. ⋯ This manuscript reviews the current information on glycation of hemoglobin, HbA1c determination methods, interferences and attempts for standardization. We aim at pointing out to the reader the current problems of glycated hemoglobin determination and to describe the necessary measures which need to be taken for proper measurement of HbA1c.
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Wien. Klin. Wochenschr. · May 2002
Severe accidental hypothermia with or without hemodynamic instability: rewarming without the use of extracorporeal circulation.
The optimal rewarming technique for patients in deep accidental hypothermia with core temperatures below 28 degrees C is not established. Several authors believe that extracorporeal rewarming is essential, especially for patients with hemodynamic instability. Others believe that invasive rewarming ought to be reserved for patients in cardiac arrest. We describe our experience with a strictly conservative technique without the use of invasive rewarming devices in patients with severe accidental hypothermia and a sustained perfusion rhythm. ⋯ A conservative approach is highly successful in achieving normothermia in patients with deep hypothermia with or without stable hemodynamics. In-hospital mortality of severe accidental hypothermia in urban conditions is high; comorbidity might play a major role. The influence of the rewarming strategy on late in-hospital mortality remains unclear.
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Wien. Klin. Wochenschr. · May 2002
Editorial Comment Comparative StudyAccidental deep hypothermia: a rewarming challenge.