Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Sep 2020
Long-term vertigo control after cochlear implantation in patients with end-stage Menière's disease : A retrospective questionnaire-based cross-sectional study.
Menière's disease (MD) is a symptom complex which is characterized by episodes of vertigo, tinnitus and fluctuating sensorineural hearing loss, which worsens during the course of the disease. ⋯ A CI can be an adequate treatment for vertigo attacks in patients with end-stage MD; however, due to the small sample size additional (multicenter) trials are necessary to confirm the findings.
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Wien. Klin. Wochenschr. · Sep 2020
Knock-on effect of periodontitis to the pathogenesis of Alzheimer's disease?
Alzheimer's disease has chronic inflammatory components, which can be enhanced by systemic immune activation resulting in inflammation or vice versa. There is growing evidence that chronic periodontitis drives systemic inflammation and finally Alzheimer's disease. Thus, a link might exist between oral pathogens and Alzheimer's disease. This may be of special significance as there is an age-related incidence of chronic periodontitis. ⋯ Data indicate a possible association of specific periodontal pathogens with cognitive impairment, Treponema denticola and Tannerella forsytia may alter the host immune response in Alzheimer's disease. Albeit still preliminary, findings of the study may point to a possible role of an altered salivary microbiome as a causal link between chronic periodontitis and cognitive impairment in Alzheimer's disease.
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Wien. Klin. Wochenschr. · Sep 2020
Randomized Controlled Trial Multicenter StudyEQ-5D-5L questionnaire as suitable assessment of quality of life after epiduroscopy : Multicenter randomized double-blind pilot study.
Epiduroscopy is a well-established diagnostic and to certain level therapeutic tool in complex situations, where conventional methods such as magnetic resonance imaging (MRI) lack power or resolution to detect pathological changes. Such a situation is primarily failed back surgery syndrome (FBSS) but also radicular pain without surgery. The aim of this study was to determine the effectiveness of epiduroscopic treatment in patients with FBSS. ⋯ Epiduroscopy appears to be a beneficial procedure for both patient groups, especially after 6 months, with some benefit remaining after 12 months. The EQ-5D-5L questionnaire seems to be a suitable and comprehensive way to assess patient health in chronic pain states.
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Wien. Klin. Wochenschr. · Sep 2020
Outcome after intravenous thrombolysis in embolic stroke of undetermined source compared to cardioembolic stroke.
It is assumed that most cases of embolic stroke of undetermined source (ESUS) are of cardioembolic origin. The data about outcome after the treatment with intravenous thrombolysis (IVT) for this type of acute ischemic stroke (AIS) are limited. We aimed to compare clinical characteristics and outcomes after IVT for AIS between patients with ESUS and cardioembolic stroke (CS). ⋯ Patients with ESUS had better outcome after IVT than patients with CS, which can be attributed to younger age and milder strokes in these patients.