Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Apr 2021
Hydroxychloroquine versus lopinavir/ritonavir in severe COVID-19 patients : Results from a real-life patient cohort.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a high mortality. To date no trial comparing hydroxychloroquine (HCQ) and lopinavir/ritonavir (LPV/RTV) has been performed. ⋯ No statistically significant differences were observed in outcome parameters in patients treated with HCQ or LPV/RTV but patients in the LPV/RTV group showed a numerically lower hospital mortality rate. Additionally, in comparison to other studies we demonstrated a lower mortality in patients treated with LPV/RTV despite having similar patient groups, perhaps due to early initiation of treatment.
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Wien. Klin. Wochenschr. · Apr 2021
6-month SARS-CoV-2 antibody persistency in a Tyrolian COVID-19 cohort.
As coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 evolved only recently, the persistency of the anti-viral antibody response remains to be determined. ⋯ There is a stable and persisting antibody response against acute respiratory syndrome coronavirus 2 at 6 months after infection. Neutralizing antibodies confirm virus specificity. As the number of coronavirus disease 2019 convalescent cases is increasing sharply, antibody testing should be implemented to identify immunized individuals. This information can be helpful in various settings of professional and private life.
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Wien. Klin. Wochenschr. · Apr 2021
Influence of age and gender on the epidemic of COVID-19 : Evidence from 177 countries and territories-an exploratory, ecological study.
The pandemic of coronavirus disease 2019 (COVID-19) is spreading worldwide with an uncertain ultimate impact on every aspect of human society. Recognizing the groups with higher susceptibility and fatality are in urgent need. ⋯ The correlation between the composition of age and gender and the epidemic characteristics of COVID-19 confirmed previous points that females are more susceptible to COVID-19. The results remind us that more attention should be paid to male patients, particularly those over 65 years old for enhanced clinical management.
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Wien. Klin. Wochenschr. · Apr 2021
Effect of early oseltamivir on outpatients without hypoxia with suspected COVID-19.
Since December 2019 coronavirus disease 2019 (COVID-19) outbreaks have occurred in China and many countries around the world. The effectiveness of oseltamivir on COVID-19 suspected outpatients without hypoxia was evaluated. ⋯ These findings suggest that early oseltamivir administration may lower the duration of fever in COVID-19 suspected outpatients without hypoxia when it is used in combination with antibacterial therapy.
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Wien. Klin. Wochenschr. · Apr 2021
[Pellagra-originally described in the Austrian Empire 250 years ago became a fatal endemic in some provinces].
Pellagra is characterized by "dermatitis - diarrhea - dementia - death". Various causes were discussed over the course of two centuries. The initial presumption was that the sun caused changes in exposed areas of the body. ⋯ It was also important to educate the population about preventing pellagra by consuming proper food. Pellagra funds to sustain the measures were established. In the provinces, pellagra commissions, chaired by the governor and consisting of twelve experts of the relevant medical branches, were appointed as an advisory and expert body.