Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jan 2024
ReviewThe three pillars in treating antibody-mediated encephalitis.
The rapid initiation of immunotherapy has a decisive impact on the course of the disease in patients with antibody-mediated encephalitis (AE). The importance of treating AE with antiseizure medication and antipsychotics is discussed controversially; however, standardized procedures should be ensured, especially for the initiation of treatment in severe disease. Recommendations and guidelines for further interventions in refractory courses are needed. In this review, we contrast the three mainstays of treatment options in patients with AE and attempt to highlight the importance of 1) antiseizure therapy, 2) antipsychotic therapy, and 3) immunotherapy/tumor resection from today's perspective.
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Wien. Klin. Wochenschr. · Jan 2024
The positive effect of spermidine in older adults suffering from dementia after 1 year.
A positive effect of the effect of a 3-month oral spermidine intake on memory performance has already been demonstrated. The continuation of this study aimed to examine whether there could be observed an improvement in memory performance after one year. ⋯ The new results confirm the already proven positive effect of oral spermidine intake on memory performance.
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Wien. Klin. Wochenschr. · Jan 2024
Subclinical atherosclerosis in patients with relapsing-remitting multiple sclerosis.
Multiple sclerosis is an inflammatory disorder of the central nervous system. Inflammation may create high susceptibility to subclinical atherosclerosis. The purpose of this study was to compare subclinical atherosclerosis and the role of inflammatory cytokines between the group of patients with relapsing-remitting multiple sclerosis (RRMS) and healthy controls matched for age and sex. ⋯ The findings of the present study suggest that when treated with DMD RRMS might not be an independent risk factor for early atherosclerosis presenting with arterial wall thickening; however, the results suggest a significant association of IL‑6 serum levels with CCA IMT only in the RRMS group.
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Wien. Klin. Wochenschr. · Jan 2024
Seasonality of benign paroxysmal positional vertigo : A retrospective study from Central Europe.
Although benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo in clinical practice, factors influencing the pathophysiology remain not fully understood. ⋯ Our results show a seasonal accumulation of BPPV during winter and springtime, which is in line with previous studies from other climatic zones, suggesting an association of this seasonality with varying vitamin D levels.