Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jan 2024
ReviewThe three pillars in treating antibody-mediated encephalitis.
The rapid initiation of immunotherapy has a decisive impact on the course of the disease in patients with antibody-mediated encephalitis (AE). The importance of treating AE with antiseizure medication and antipsychotics is discussed controversially; however, standardized procedures should be ensured, especially for the initiation of treatment in severe disease. Recommendations and guidelines for further interventions in refractory courses are needed. In this review, we contrast the three mainstays of treatment options in patients with AE and attempt to highlight the importance of 1) antiseizure therapy, 2) antipsychotic therapy, and 3) immunotherapy/tumor resection from today's perspective.
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Wien. Klin. Wochenschr. · Jan 2024
The positive effect of spermidine in older adults suffering from dementia after 1 year.
A positive effect of the effect of a 3-month oral spermidine intake on memory performance has already been demonstrated. The continuation of this study aimed to examine whether there could be observed an improvement in memory performance after one year. ⋯ The new results confirm the already proven positive effect of oral spermidine intake on memory performance.
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Wien. Klin. Wochenschr. · Jan 2024
Seasonality of benign paroxysmal positional vertigo : A retrospective study from Central Europe.
Although benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo in clinical practice, factors influencing the pathophysiology remain not fully understood. ⋯ Our results show a seasonal accumulation of BPPV during winter and springtime, which is in line with previous studies from other climatic zones, suggesting an association of this seasonality with varying vitamin D levels.
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Wien. Klin. Wochenschr. · Jan 2024
The Vienna idiopathic intracranial hypertension database-An Austrian registry.
Idiopathic intracranial hypertension (IIH) is becoming increasingly more prevalent bearing the risk of visual impairment and affecting the quality of life. Clinical presentation and outcome are heterogeneous. Large, well-characterized cohorts are scarce. ⋯ The large representative Vienna IIH cohort characterizes IIH-related symptoms, diagnostic findings, treatment, and outcome emphasizing substantial long-term sequelae of IIH. Future analyses will aim to refine phenotyping and identify factors predicting outcome.