Military medicine
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Side-effects and immunogenicity of the Haemophilus influenzae type B polysaccharide vaccine (Hbpv) were reported following introduction in a multi-ethnic border population of 2- to 6-year-old U. S. military dependents. Eighty percent of 659 vaccinees were reported by parents to have no reactions within 48 hours following vaccination; 20% were reported to have local and/or systemic reactions. ⋯ Of the 114 vaccines with serologic data, those with side-effects had serologic changes comparable to those without side-effects. There was no difference in side-effects or immunologic response across ethnic groups. Therefore, side-effects, immunologic responses, and ethnic group appear to be independent variables.