[Rinshō ketsueki] The Japanese journal of clinical hematology
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Case Reports
Successful switching from eltrombopag to romiplostim in a pediatric patient with refractory chronic ITP.
Herein, we report a successful treatment experience with romiplostim in a child with immune thrombocytopenia (ITP) refractory to eltrombopag. A 9-year-old female developed chronic ITP, which was refractory to standard treatments, including intravenous immunoglobulin, cepharanthine and splenectomy, and she thus became dependent on prednisolone (PSL). ⋯ Platelet counts increased and PSL could thus be terminated. Our case suggests TPO-RA alteration to potentially be effective for chronic refractory ITP.