International journal of dermatology
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Randomized Controlled Trial
Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation.
Ivermectin is a broad-spectrum parasiticide in widespread systemic use, including as an off-label treatment for head lice infestation. The potential of the topical use of ivermectin as a treatment for head lice infestation was suggested by an in vitro report of a novel lotion formulation. ⋯ A single application of a 0.5% concentration of this ivermectin lotion formulation shows promise as a safe and effective treatment for head lice infestation and the associated signs of pruritus.