Indian pediatrics
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Editorial Comment
Oxygen therapy during neonatal resuscitation--too little or too much?
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Review Meta Analysis
Safety of oral use of nimesulide in children: systematic review of randomized controlled trials.
Nimesulide has been widely used to treat fever in children. Due to reports of adverse drug reactions, discontinuation or modification of its use has been suggested. ⋯ Oral nimesulide is as safe or unsafe as other analgesics-antipyretics for short-term use (less than or equal to 10 d) in children. The drug is best avoided in known or suspected liver disease; caution is warranted while prescribing nimesulide concomitantly with other hepatotoxic drugs. There is limited data for drawing concrete inferences below the age of six months.