Indian pediatrics
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he present study is an attempt to evaluate the clinical manifestations of severe scorpion sting in children and their management at a rural setting. Twelve patients with severe scorpion sting referred from primary health center are presented in this report. Eight children had pulmonary edema and hypotension; two had pulmonary edema and hypertension while one each presented with hypertension and tachycardia in isolation. ⋯ Two children died of massive pulmonary edema despite use of SNP and dopamine drip. Anti scorpion venom did not prevent the cardiovascular manifestations of severe scorpion sting. Early administration of prazosin alleviated the severity of scorpion envenomation
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Editorial Comment
Oxygen therapy during neonatal resuscitation--too little or too much?
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Review Meta Analysis
Safety of oral use of nimesulide in children: systematic review of randomized controlled trials.
Nimesulide has been widely used to treat fever in children. Due to reports of adverse drug reactions, discontinuation or modification of its use has been suggested. ⋯ Oral nimesulide is as safe or unsafe as other analgesics-antipyretics for short-term use (less than or equal to 10 d) in children. The drug is best avoided in known or suspected liver disease; caution is warranted while prescribing nimesulide concomitantly with other hepatotoxic drugs. There is limited data for drawing concrete inferences below the age of six months.