Journal of insect physiology
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We examined physiological phenotypes of Drosophila melanogaster in hypoxic to hyperoxic atmospheres. We performed measurements on life span or behavioural function in 5, 21, 40, 60, and 80% O(2), and combined this with literature data for 2% and 100% O(2). O(2) incubation resulted in a concentration-dependent reduction of life span in both hypoxia and hyperoxia, though different measures of life span were affected differently. ⋯ Because ageing results in generally irreversible functional declines, we examined if functional declines in hyperoxia (60% O(2)) were also irreversible, or whether some functioning could recover after a return to normoxia. After 7 days of recovery, water loss rates decreased, CO(2) exhalation slightly increased, and climbing ability was partially recovered. Therefore, the effect of O(2) on D. melanogaster function is non-linear, may be reversible, and may include unique phenotypes that arise at some O(2) concentrations, and not others.