Headache
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Randomized Controlled Trial Clinical Trial
Botulinum toxin type A as a migraine preventive treatment. For the BOTOX Migraine Clinical Research Group.
To assess the safety and efficacy of botulinum toxin type A (BOTOX; Allergan, Inc) in the prevention of migraine. ⋯ Pericranial injection of botulinum toxin type A, 25 U, was found to be a safe treatment that significantly reduced migraine frequency, migraine severity, acute medication usage, and associated vomiting.