Headache
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Randomized Controlled Trial Comparative Study Clinical Trial
Intravenous dipyrone in the acute treatment of migraine without aura and migraine with aura: a randomized, double blind, placebo controlled study.
Dipyrone (Metamizol) has been used in the acute treatment of migraines in Brazil. Some investigators have found it to be a highly effective medication for migraine pain and associated symptoms. ⋯ Dipyrone is an effective drug for the relief of acute migraine pain and associated symptoms.
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Randomized Controlled Trial Comparative Study Clinical Trial
Migraine with aura versus migraine without aura: pain intensity and associated symptom intensities after placebo.
To compare the intensity of pain and associated symptoms after placebo administration in patients with migraine with aura and migraine without aura. ⋯ Our findings suggest that studies comparing placebo against an active drug should use stratification according to the presence versus absence of aura.
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To review psychiatric issues that accompany migraine and means of addressing these issues. ⋯ Migraine is often comorbid with psychiatric disorders, particularly depression and anxiety. The relationship is likely based on shared mechanisms and successful treatment is possible.