Gut
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Review Meta Analysis
Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis.
There has been no definitive systematic review and meta-analysis to date examining the effect of laxatives and pharmacological therapies in chronic idiopathic constipation (CIC). ⋯ Laxatives, prucalopride, lubiprostone and linaclotide are all more effective than placebo for the treatment of CIC.