Journal of behavior therapy and experimental psychiatry
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Nocebo hyperalgesia (i.e., increased pain sensitivity based on expectations) can be induced by conditioning, but is supposed to be mediated by conscious expectation. Although recent evidence points to the feasibility of subliminal conditioning of nocebo hyperalgesia with masked faces, face processing might be a special case and the practical implications of subliminal conditioning remain questionable. This study aimed to implicitly condition nocebo hyperalgesia using supraliminal cues. ⋯ The results support the notion that implicit conditioning of nocebo hypoalgesia is feasible using a novel experimental conditioning design with supraliminal stimulus presentation, although further research is needed. So far, implicitly conditioned nocebo effects might have been underestimated despite vast clinical implications.