Archives of physical medicine and rehabilitation
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Arch Phys Med Rehabil · Jun 1996
Randomized Controlled Trial Clinical TrialSubacute methylphenidate treatment for moderate to moderately severe traumatic brain injury: a preliminary double-blind placebo-controlled study.
To determine the effect of subacute administration of methylphenidate on recovery from moderate to moderately severe closed head injury. ⋯ Subacute administration of methylphenidate after moderately severe head injury appeared to enhance the rate but not the ultimate level of recovery as measured by the DRS and tests of vigilance. Problems with possible selection bias and small sample size limit generalization of results.