Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Mar 2008
Mild traumatic brain injury does not predict acute postconcussion syndrome.
The aetiology of postconcussion syndrome (PCS) following mild traumatic brain injury (mTBI) remains controversial. Identifying acute PCS (within the first 14 days after injury) may optimise initial recovery and rehabilitation, identify those at risk and increase understanding of PCS. ⋯ There is a high rate of acute PCS in both mTBI and non-brain injured trauma patients. PCS was not found to be specific to mTBI. The use of the term PCS may be misleading as it incorrectly suggests that the basis of PCS is a brain injury.
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J. Neurol. Neurosurg. Psychiatr. · Mar 2008
Case ReportsNeurological response to early removal of ovarian teratoma in anti-NMDAR encephalitis.
We report an 18-year-old woman with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, who developed psychiatric symptoms, progressive unresponsiveness, dyskinesias, hypoventilation, hypersalivation and seizures. Early removal of an ovarian teratoma followed by plasma exchange and corticosteroids resulted in a prompt neurological response and eventual full recovery. ⋯ The patients' antibodies reacted with areas of the tumour that contained NMDAR-expressing tissue. Search for and removal of a teratoma should be promptly considered after the diagnosis of anti-NMDAR encephalitis.
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J. Neurol. Neurosurg. Psychiatr. · Mar 2008
Randomized Controlled TrialGabapentin for prevention of hypobaric hypoxia-induced headache: randomized double-blind clinical trial.
High-altitude headache (HAH) is a hypobaric hypoxia-induced symptom that is commonly experienced by newcomers to high-altitude areas. ⋯ Gabapentin was effective for the prevention of HAH and had satisfactory tolerability.