Journal of neurology, neurosurgery, and psychiatry
-
J. Neurol. Neurosurg. Psychiatr. · Nov 2009
Randomized Controlled TrialS-100B and neuron specific enolase are poor outcome predictors in severe traumatic brain injury treated by an intracranial pressure targeted therapy.
To prospectively study S-100B and neuron specific enolase (NSE) levels in subjects treated for severe head injury (sTBI), and investigate the prognostic value of these biomarkers. ⋯ At 3 and 12 months after trauma, no differences in prognostic values between the markers were apparent nor was there any clinical significant value of the markers as predictors of clinical outcome.
-
J. Neurol. Neurosurg. Psychiatr. · Nov 2009
Cognitive impairment predicts poststroke death in long-term follow-up.
Poststroke global cognitive decline and dementia have been related to poor long-term survival. Whether deficits in specific cognitive domains are associated with long-term survival in patients with ischaemic stroke is not known in detail. ⋯ In patients with ischaemic stroke, cognitive impairment, particularly in executive functions, and visuospatial/constructional abilities relate to poor survival.
-
J. Neurol. Neurosurg. Psychiatr. · Nov 2009
Case ReportsThe neural basis of effective memory therapy in a patient with limbic encephalitis.
An fMRI study is described in which a postencephalitic woman with amnesia used a wearable camera which takes photographs passively, without user intervention, to record and review recent autobiographical events. "SenseCam" generates hundreds of images which can subsequently be reviewed quickly or one by one. ⋯ SenseCam images may provide powerful cues that trigger the recall and consolidation of stored but inaccessible memories.
-
J. Neurol. Neurosurg. Psychiatr. · Nov 2009
Periodontitis is associated with cognitive impairment among older adults: analysis of NHANES-III.
Periodontitis is ubiquitous and associated with serological evidence of exposure to periodontal organisms, systemic inflammation and vascular disease. Dementia is a major public health problem likely related to a complex interaction between genetics and diseases associated with systemic inflammation, including diabetes, smoking and stroke. ⋯ A serological marker of periodontitis is associated with impaired delayed memory and calculation. Further exploration of relationships between oral health and cognition is warranted.