European journal of clinical investigation
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Eur. J. Clin. Invest. · Oct 2020
Prevalence and control of hypertension among patients on hemodialysis.
Earlier studies provided considerably variable estimates on the prevalence and control rates of hypertension in haemodialysis because of their heterogeneity in definitions and blood pressure (BP) measurement techniques applied to detect hypertension. ⋯ This study shows that the prevalence, but mainly the control rates of hypertension in patients on haemodialysis, differs between peridialytic and interdialytic BP recordings. Therefore, the wider use of home BP monitoring may improve the determination of BP control status in this high-risk population.
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Eur. J. Clin. Invest. · Oct 2020
Review Meta AnalysisAssociation between diabetes mellitus and lung cancer: meta-analysis.
This study aimed to summarize the association between diabetes mellitus (DM) and the incidence of lung cancer using a meta-analysis of cohort studies. ⋯ This meta-analysis suggests that DM has no significant impact on the incidence of lung cancer in men but has a harmful effect on women.
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Eur. J. Clin. Invest. · Oct 2020
Meta AnalysisPredictors of Adverse Prognosis in Covid-19: A Systematic Review and Meta-analysis.
Identification of reliable outcome predictors in coronavirus disease 2019 (COVID-19) is of paramount importance for improving patient's management. ⋯ Advanced age, comorbidities, abnormal inflammatory and organ injury circulating biomarkers captured patients with an adverse clinical outcome. Clinical history and laboratory profile may then help identify patients with a higher risk of in-hospital mortality.
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Eur. J. Clin. Invest. · Oct 2020
ReviewGenetic Predisposition in Metabolic-Dysfunction-Associated Fatty Liver Disease and Cardiovascular Outcomes - Systematic Review.
Despite the demonstrated increased cardiovascular (CV) risk associated with metabolic-dysfunction-associated fatty liver disease (MAFLD), genetic variants predisposing to MAFLD were not constantly associated with CV events. Recently, rs641738C > T near membrane-bound O-acyltransferase domain-containing 7 (MBOAT7) has been studied in MAFLD and CV outcomes. Therefore, we aimed to evaluate the association between rs641738C > T in the presence and severity of hepatic steatosis, fibrosis, biochemical markers and progression to hepatocellular carcinoma (HCC), in addition to CV outcomes in MAFLD. ⋯ Despite inconclusive results in Asian populations, rs641738C > T near MBOAT7 is associated with increased hepatic fat, MAFLD severity, susceptibility to develop NASH, advanced fibrosis and HCC in adults from Caucasian, Hispanic and African American ethnicities with MAFLD, as well as elevated ALT levels in children, while exerting neutral effects in CAD.
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Eur. J. Clin. Invest. · Oct 2020
ReviewEpidemiology, Clinical Characteristics of the First Cases of COVID-19.
COVID-19 is currently the most urgent threat to public health in the world. The aim of this study is to provide an overview of the first cases of COVID-19 to make further improvements in health policies and prevention measurements in response to the outbreak of COVID-19. ⋯ Understanding the epidemiological characteristics, clinical characteristics, and diagnosis and treatment of the first patients in various countries are of great significance for the identification, prevention and control of COVID-19.