European journal of clinical investigation
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Eur. J. Clin. Invest. · Apr 2021
Review Meta AnalysisEffect of low-dose colchicine in acute and chronic coronary syndromes.
Sparse evidence of the prognostic benefit of the anti-inflammatory drug colchicine in chronic and acute coronary syndromes (CCS/ACS) exists. ⋯ Colchicine therapy near halves the risk of cardiovascular events in CCS compared with placebo and is associated with a nonsignificant 23% risk reduction in ACS, together with a trend towards a greater reduction of hs-CRP.
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Eur. J. Clin. Invest. · Apr 2021
Temporal trends in cardiovascular risk factors prevalence in patients with myocardial infarction.
Little is known about changes in cardiovascular risk factors (CVRF) profile over time in patients presenting with acute myocardial infarction (AMI). ⋯ Among patients with AMI in Switzerland over two decades, age at presentation remained stable, while the mean number of CVRF increased in both men and women. Striking was the increase in the prevalence of smoking in women, leading to a reduction of the gender gap over time.